Organotin Reagent Toxicity
The main damages of organotin compounds to organisms are: the central nervous system can cause cerebral white matter edema, the process of oxidative phosphorylation in the energy utilization of cells is hindered, the thymus and lymph Inhibition of the system, impairment of cellular immunity, and inhibition of hormone secretion cause diabetes and hyperlipidemia. Toxicity to humans, local irritation to the skin, respiratory tract, and cornea, systemic poisoning and even death through skin or brain edema. Different types of organotin reagents have varying degrees of toxicity. Long-term low-dose exposure to organotin compounds can cause negative health effects in humans, including damage to the liver and nervous system, as well as reproductive and developmental problems.
For example, the organotin compound tributyltin compound can absorb or inhale vapors through the skin Entering the human body, it will cause harm to the nervous system, immune system and reproductive system of the human body, and may even cause certain types of cancer. Similarly, organotin oxides, such as hexamethylbis(bisphenoxy)tin, can also cause damage to the human respiratory system, digestive system and muscular system.
Therefore, when using organotin reagents, safety operating procedures should be followed and strengthened Pay attention to protective measures. Take care to avoid inhalation, skin contact and ingestion during use. Operation in a well-ventilated environment is required to prevent inhalation of organotin compound vapors and dust. At the same time, corresponding measures should be taken when disposing of organotin reagent waste to prevent adverse effects on the environment.